ECM1 antibody
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- Target See all ECM1 Antibodies
- ECM1 (Extracellular Matrix Protein 1 (ECM1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ECM1 antibody is un-conjugated
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Application
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificity
- This MAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.
- Cross-Reactivity (Details)
- Human and Rat.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Full length native protein (purified) corresponding to Human IgA Secretory Component. Affinity-purified secretory component from human colostrum.
- Clone
- SC05
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product ECM1 Primary Antibody
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- Application Notes
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Known_Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: Stomach, Lung, or Breast tumor.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- ECM1 (Extracellular Matrix Protein 1 (ECM1))
- Alternative Name
- ECM1 (ECM1 Products)
- Synonyms
- URBWD antibody, ECM antibody, EMILIN4 antibody, GPIa* antibody, MMRN antibody, AI663821 antibody, p85 antibody, extracellular matrix protein 1 antibody, multimerin 1 antibody, ECM1 antibody, MMRN1 antibody, Ecm1 antibody
- Background
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ECM1, Extracellular Matrix Protein 1, Secretory Component p85, URBWD,IgA Secretory Component / ECM1
Cellular localisation: Cell surface. Cytoplasm. - Molecular Weight
- ~80kDa
- Gene ID
- 1893, 81071
- UniProt
- Q16610
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