ENAH antibody (AA 485-589)

Catalog No. ABIN6937147

This anti-ENAH antibody is a Mouse Monoclonal antibody detecting ENAH in WB, ELISA and Coat. Suitable for Human.

Quick Overview for ENAH antibody (AA 485-589) (ABIN6937147)

Target: ENAH (Enabled Homolog (ENAH))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ENAH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Coating (Coat)

Clone: ENAH-1988

Product Details anti-ENAH Antibody

Binding Specificity: AA 485-589

Specificity: The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. WASP is a downstream effector of Cdc42 and has been implicated in actin polymerization and cyto- skeletal organization. Distantly related proteins, VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), are involved in the regulation of cytoskeletal dynamics. Both Mena and VASP accumulate at focal adhesions. Mena is highly expressed in the developing nervous system and may be involved in growth cone motility and axon guidance.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment of human MENA protein (around aa 485-589) (exact sequence is proprietary)

Isotype: IgG2c kappa

Application Details

Application Notes:

Known_Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: MCF-7 cells. Uterus.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for ENAH

Target: ENAH (Enabled Homolog (ENAH))

Alternative Name: ENAH

Background: ENA, ENAH, MENA, NDPP1,ENAH / MENA (Actin Regulator)
Cellular localisation: Cytoplasmic

Molecular Weight: 80/88/140kDa

Gene ID: 55740, 497893

UniProt: Q8N8S7