EPX antibody

Catalog No. ABIN6937163

This Mouse Monoclonal antibody specifically detects EPX in IF and FACS. It exhibits reactivity toward Human.

Quick Overview for EPX antibody (ABIN6937163)

Target: EPX (Eosinophil Peroxidase (EPX))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPX antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: AHE-1

Product Details anti-EPX Antibody

Purpose: Eosinophil Peroxidase (EPX) Antibody

Specificity: Peripheral blood granulocytes are classified into neutrophils, basophils and eosinophils according to the staining characteristics of their cytoplasmic granules. Granule proteins are released by physiologic and pharmacologic stimuli and play important roles in both normal and pathological host immune responses. Eosinophil major basic protein and eosinophil peroxidase (EPX) are granule proteins specific to the eosinophil. AHE-1 recognizes human EPX, a granule protein specific to eosinophils. It does not cross-react with eosinophil major basic protein, elastase, cathepsin G, esterase N, thrombin, plasmin, kallikrein, lactoferrin, or transferrin. This MAb stains eosinophils only and does not stain other peripheral blood cells, including platelets, neutrophils, monocytes, lymphocytes or red blood cells. Human EPX gene product can form a tetramer of two light chains and two heavy chains. Other peroxidase family members include myeloperoxidase (MPO), lactoperoxidase (LPO), and thyroid peroxidase (TPO).

Cross-Reactivity (Details): Human.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Human eosinophils from a patient with hypereosinophilic syndrome

Isotype: IgG1, kappa

Application Details

Application Notes:

Known_Application: ELISA (For coating, order antibody without BSA),Optimal dilution for a specific application should be determined.

Positive_Control: MCF-7 cells. Tonsil.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for EPX

Target: EPX (Eosinophil Peroxidase (EPX))

Alternative Name: EPX

Background:

Eosinophil peroxidase heavy chain, EPER, EPO, EPP, EPX, EPX PEN, PERE

MCF-7 cells. Tonsil

Molecular Weight: 70kDa (55kDa-Heavy Chain, 15kDa-Light Chain)

UniProt: P11678