Recombinant F13A1 antibody (AA 46-181)

Catalog No. ABIN6937207

The Rabbit Monoclonal anti-F13A1 antibody (Clone F13A1-3772R) (ABIN6937207) specifically detects F13A1 in IHC. The antibody is reactive with Human samples.

Quick Overview for Recombinant F13A1 antibody (AA 46-181) (ABIN6937207)

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This F13A1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: F13A1-3772R

Product Details anti-F13A1 Antibody

Binding Specificity: AA 46-181

Purpose: Recombinant Factor XIIIa (Coagulation Factor XIIIA Chain) Antibody

Specificity: It recognizes a protein of 83 kDa, which is identified as Factor XIIIa. It has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-factor XIIIa has been found to be useful in differentiating between dermatofibroma (almost all cases are positive), dermatofibrosarcoma protuberans (-/+) and desmoplastic malignant melanoma (-). Anti-factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor, and meningioma.

Cross-Reactivity (Details): Human.

Purification: 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system.

Immunogen: Recombinant fragment of human Factor XIIIa protein (aa46-181) (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT) ,(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Human placenta tissue (IHC).

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for F13A1

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Alternative Name: F13A1

Background:

Coagulation factor XIII A chain, Coagulation factor XIII A1 polypeptide, F13A, F13a1, Fibrin stabilizing factor, A subunit, Fibrinoligase, FSF, A subunit, Protein-glutamine gamma-glutamyltransferase A chain, TGase, Transglutaminase. plasma

Human placenta tissue (IHC).

Molecular Weight: 83kDa

Gene ID: 2162, 335513

UniProt: P00488