FGA antibody
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- Target See all FGA Antibodies
- FGA (Fibrinogen alpha Chain (FGA))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This FGA antibody is un-conjugated
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Application
- ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)
- Specificity
- The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits: . Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.
- Cross-Reactivity (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Human acute monoblastic leukemia cells.
- Clone
- UC45
- Isotype
- IgM kappa
- Top Product
- Discover our top product FGA Primary Antibody
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- Application Notes
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Known_Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: Plasma.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Purified Ab WITHOUT BSA at 1.0mg/ml
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- FGA (Fibrinogen alpha Chain (FGA))
- Alternative Name
- FGA (FGA Products)
- Synonyms
- Fib2 antibody, ENSMUSG00000059807 antibody, Fib antibody, Ac1873 antibody, Fba5e antibody, fibrinogen alpha chain antibody, FGA antibody, Fga antibody, LOC698244 antibody
- Background
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Ac1873, Fba5e, FGA, Fib, Fib2, Fibrinogen alpha chain, Fibrinogen, A alpha polypeptide, Fibrinogen--alpha polypeptide chain, Fibrinopeptide A,Fibrinogen Alpha Chain
Cellular localisation: Secreted. - Molecular Weight
- 30kDa
- Gene ID
- 2243, 351593
- UniProt
- P02671
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