GATA3 antibody (AA 357-436)
Quick Overview for GATA3 antibody (AA 357-436) (ABIN6937305)
Target
See all GATA3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 357-436
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Purpose
- GATA-3 (Breast and Urothelial Marker) Antibody
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Specificity
- GATA-3 is a zinc finger transcription factor and plays an important role in promoting and directing cell proliferation, development, and differentiation in many tissues and cell types. GATA-3 expression is primarily seen in breast and urothelial carcinomas.'Therefore, GATA3 antibody can be useful in the identification of unknown primary carcinoma when carcinomas of the breast or bladder are a possibility.
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Cross-Reactivity (Details)
- Human.
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Purification
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant fragment of human GATA3 protein (around aa 357-436) (exact sequence is proprietary)
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Isotype
- IgG1, kappa
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Application Notes
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Known_Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7 or T47D cells. Breast or Bladder Carcinoma.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Preservative
- Azide free
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Storage
- -20 °C,-80 °C
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Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Expiry Date
- 24 months
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- GATA3 (GATA Binding Protein 3 (GATA3))
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Alternative Name
- GATA3
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Background
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GATA3, GATA binding protein-3, GATA-binding factor 3, GATA3, HDR, HDRS, Transacting T-cell-specific transcription factor GATA-3
MCF-7 or T47D cells. Breast or Bladder Carcinoma.
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Molecular Weight
- ~50kDa
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Gene ID
- 2625, 524134
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UniProt
- P23771
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Pathways
- Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
Target
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