HLA-ABC antibody
Quick Overview for HLA-ABC antibody (ABIN6937393)
Target
See all HLA-ABC AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
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Cross-Reactivity (Details)
- Human. Mouse. Non-Human primates.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
- Human peripheral blood leukocytes
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Isotype
- IgG2a kappa
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anti-HLA-ABC (HLA-ABC) antibody
HLA-ABC Reactivity: Human, Cow, Baboon, Cat, Monkey FACS, IP, IHC (fro), WB, IHC Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibody (PE)HLA-ABC Reactivity: Human, Cow, Baboon, Cynomolgus, Rhesus Monkey, Macaque, Shrew, Chimpanzee, Gorilla FACS Host: Mouse Monoclonal W6-32 PE
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC Reactivity: Human, Cow, Cat, Monkey, Primate FACS, IP, IHC (fro), IF, EIA Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC Reactivity: Human, Cow, Baboon, Macaque, Cat, Monkey, Primate, Chimpanzee FACS, IP, IHC (fro), IF, Func, EIA, DNA Mic Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibodyGMP Grade HLA-ABC Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey FACS Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibody (FITC)GMP Grade HLA-ABC Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey FACS Host: Mouse Monoclonal W6-32 FITC
anti-HLA-ABC (HLA-ABC) antibody (PE)GMP Grade HLA-ABC Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey FACS Host: Mouse Monoclonal W6-32 PE
anti-HLA-ABC (HLA-ABC) antibody (APC)GMP Grade HLA-ABC Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey FACS Host: Mouse Monoclonal W6-32 APC
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Application Notes
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: THP-1 and Jurkat cells. Tonsil or lymph node.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Preservative
- Azide free
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Storage
- -20 °C,-80 °C
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Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Expiry Date
- 24 months
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- HLA-ABC
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Alternative Name
- HLA-A, HLA-B, HLA-C
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Background
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HLA-A, HLA-B, HLA-C, HLA class 1A, HLA class 1B, HLA class 1C, Major histocompatibility complex, class I, A + B + C, MHC class I HLA-A, MHC class I HLA-B, MHC class I HLA-C, MHC HLA-ABC,HLA-ABC (MHC I)
Cellular localisation: Cell surface -
Molecular Weight
- ~41kDa
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Gene ID
- 3105, 3106, 3107
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UniProt
- P01889, P30443, P30499
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Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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