Recombinant IGHG antibody

Catalog No. ABIN6937503

The Rabbit Monoclonal anti-IGHG antibody is suitable to detect IGHG in samples from Human. It has been validated for StM.

Quick Overview for Recombinant IGHG antibody (ABIN6937503)

Target: IGHG (Immunoglobulin Heavy Chain (Gamma Polypeptide) (IGHG))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IGHG antibody is un-conjugated

Application: Staining Methods (StM)

Clone: IG507R

Product Details anti-IGHG Antibody

Specificity: Recognizes a protein of 75 kDa, identified as gamma heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin s lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human IGHG protein

Isotype: IgG

Application Details

Application Notes:

Known_Application: Known Applications &Suggested DilutionsImmunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Positive_Control: 293T, Raji or hPBL cells. Human tonsil or spleen.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for IGHG

Target: IGHG (Immunoglobulin Heavy Chain (Gamma Polypeptide) (IGHG))

Alternative Name: IGHG

Background: G1m Marker, G2m Marker, G3m Marker, G4m Marker, HDC, Heavy Chain Disease Protein, Human Immunglobulin G, Ig gamma1/2/3/4 Chain C Region, IGHG1, IGHG2, IGHG3, IGHG4, Immunoglobulin Heavy Constant 1/2/3/4,IgG (Immunoglobulin Gamma Heavy Chain) (IGHG) (B-Cell Marker)
Cellular localisation: Cytoplasm. Cell Surface. Secreted.

Molecular Weight: 75kDa

Gene ID: 510635

UniProt: P01857, P01859, P01860, P01861