IL-4 antibody

Catalog No. ABIN6937554

The Rat Monoclonal anti-IL-4 antibody has been validated for ELISA, FACS, Neut, IF and Coat. It is suitable to detect IL-4 in samples from Mouse.

Quick Overview for IL-4 antibody (ABIN6937554)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-4 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Neutralization (Neut), Immunofluorescence (IF), Coating (Coat)

Clone: 11B11

Product Details anti-IL-4 Antibody

No Cross-Reactivity: Human

Purification: Purified by Protein A/G

Immunogen: Partially Purified native Mouse IL-4

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: Spleen, Thymus or Lymph Node.

Known Application: ELISA (For coating, order Ab without BSA & Azide),Neutralization Studies (Order Ab without BSA & Azide),Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Buffer: 10 mM PBS without BSA and without Azide.

Preservative: Azide free

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.

Expiry Date: 24 months

Target Details for IL-4

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Alternative Name: IL-4 (Interleukin-4)

Background: IL-4 is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. IL-4 is a potent lymphoid cell growth factor, which stimulates the growth and activation of certain B cells and T cells. IL-4 is important for regulation of T helper subset development. IL-4 is expressed primarily by activated Th2 cells and NK cells, and at lower levels by mast cells, and basophils. IL-4 signals through the IL-4R, and dendritic cell IL-12.

Molecular Weight: 13-14kDa

Gene ID: 16189

UniProt: P07750

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation