JUP antibody

Catalog No. ABIN6937613

This Mouse Monoclonal antibody specifically detects JUP in WB, IF and FACS. It exhibits reactivity toward Chicken.

Quick Overview for JUP antibody (ABIN6937613)

Target: JUP (Junction Plakoglobin (JUP))

Reactivity: Chicken

Host: Mouse

Clonality: Monoclonal

Conjugate: This JUP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 15F11

Product Details anti-JUP Antibody

Specificity: It recognizes a protein of 80-87kDa, identified as gamma-catenin. The catenins (-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer's disease (LOAD) as well as to dilated cardiomyopathy.

Cross-Reactivity (Details): Human. Mouse. Cat. Rat. Chicken. Cow. Dog.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant, full length chicken Catenin gamma protein

Isotype: IgG1 kappa

Application Details

Application Notes:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: HeLa, SK-BR3, A431, HT20, 293, HepG2, A549 or MCF-7 cells. Skin.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for JUP

Target: JUP (Junction Plakoglobin (JUP))

Alternative Name: JUP

Background: ARVD12, Catenin (cadherin-associated protein), gamma 80 kDa, Catenin gamma, CTNNG, Desmoplakin III, Desmoplakin-3, DP3, DPIII, Junction Plakoglobin, PDGB, PKGB,Catenin, gamma (Cardiomyocyte Marker)
Cellular localisation: Cell Surface and Cytoplasmic

Molecular Weight: 80-87kDa

Gene ID: 3728, 514174

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location