Recombinant LMO2 antibody (AA 23-140)

Catalog No. ABIN6937788

The Rabbit Monoclonal anti-LMO2 antibody is suitable to detect LMO2 in samples from Human. It has been validated for WB, FACS and IF.

Quick Overview for Recombinant LMO2 antibody (AA 23-140) (ABIN6937788)

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This LMO2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: LMO2-3147R

Product Details anti-LMO2 Antibody

Binding Specificity: AA 23-140

Purpose: Recombinant LMO2 (B-Cell Marker) Antibody

Specificity: The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. It has a particular function in normal and lymphatic endothelial cells involving the regulation of angiogenesis and lymph-angiogenesis. Immunohistochemical studies have also demonstrated expression of LMO2 in both normal germinal center B-cells and germinal center-derived B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma.The use of anti-LMO2 is valuable as a tool in the identification of lymphomas of B-cell origin. LMO2 is useful in differentiating follicular lymphoma (LMO2+) from nodal marginal zone lymphoma (LM02-). It also is positive in Hodgkin s and Burkitt s lymphomas.

Cross-Reactivity (Details): Human.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa 23-140) human LMO2 protein (exact sequence is proprietary)

Isotype: IgG, kappa

Application Details

Application Notes:

Known_Application: Flow Cytometry (1-2ug/million cells); ,Immunofluorescence (1-2ug/ml);,Optimal dilution for a specific application should be determined.

Positive_Control: K562, Ramos or Raji cells. Placenta, Pancreas or Hodgkin's lymphoma

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for LMO2

Target: LMO2 (LIM Domain Only 2 (Rhombotin-Like 1) (LMO2))

Alternative Name: LMO2

Background:

Cysteine-rich protein TTG-2, LIM domain only protein 2, LMO-2, RBTN L1, RBTN2, Rhombotin like 1, Rhombotin-2 (RHOM2), T-cell translocation protein 2, TTG2

K562, Hodgkin s lymphoma, Ramos or Raji cells. Human placenta, pancreas, Brain, Human Skeletal Muscle

Molecular Weight: 24kDa

Gene ID: 4005, 34560

UniProt: P25791

Pathways: Chromatin Binding