S100A2 antibody

Catalog No. ABIN6938332

Product Details anti-S100A2 Antibody

Target: S100A2 (S100 Calcium Binding Protein A2 (S100A2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This S100A2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificity: S100A2 belongs to the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A2 may function as a modulator against excess calcium accumulation in normal human mammary epithelial cells and also have a role in suppressing tumor cell growth. This protein may have a tumor suppressor function. Chromosomal rearrangements and altered expression of this gene have been implicated in breast cancer. Cytoplasmic overexpression may also be of prognostic significance when observed in oral cancer patients, and the S100A2 has also been identified as significantly down-regulated in gastric cancer.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human S100A2 protein

Clone: CPTC-S100A2-2

Isotype: IgG2b kappa

Application Details

Application Notes:

Known_Application: Western Blot (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: HeLa. A549, HACAT, BxPC3 and A431 cell lysates, Skin and squamous cell cervical carcinoma.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for S100A2

Target: S100A2 (S100 Calcium Binding Protein A2 (S100A2))

Alternative Name: S100A2 (S100A2 Products)

Synonyms: S100A2 antibody, CAN19 antibody, S100L antibody, CaN19 antibody, EG628324 antibody, S100 calcium binding protein A2 antibody, S100A2 antibody, S100a2 antibody

Background: CAN19, MGC111539, S100L,S100A2 / S100 Calcium Binding Protein A2
Cellular localisation: Nucleus and cytoplasm.

Molecular Weight: 11.12kDa

Gene ID: 6273, 516484

UniProt: P29034

Pathways: S100 Proteins