TACSTD2 antibody (AA 31-274)

Catalog No. ABIN6938498

This Mouse Monoclonal antibody specifically detects TACSTD2 in WB and IHC (f). It exhibits reactivity toward Human.

Quick Overview for TACSTD2 antibody (AA 31-274) (ABIN6938498)

Target: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TACSTD2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: TACSTD2-2151

Product Details anti-TACSTD2 Antibody

Binding Specificity: AA 31-274

Specificity: TACSTD2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment of human TACSTD2 protein (around aa 31-274) (exact sequence is proprietary)

Isotype: IgG2b kappa

Application Details

Application Notes:

Known_Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: HT29 cells. Human breast or colon carcinoma.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for TACSTD2

Target: TACSTD2 (Tumor-Associated Calcium Signal Transducer 2 (TACSTD2))

Alternative Name: TACSTD2

Background: Cell surface glycoprotein Trop-2, Membrane Component Chromosome 1, Surface Marker 1 (M1S1), Pancreatic Carcinoma Marker Protein GA733-1, TROP2, Tumor-Associated Calcium Signal Transducer 2 (TACSTD2),TACSTD2 / TROP2 (Epithelial Marker)
Cellular localisation: Cell Surface

Molecular Weight: 40kDa

Gene ID: 4070, 23582

UniProt: P09758