TCL1A antibody (AA 2-109)
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- Target See all TCL1A Antibodies
- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
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Binding Specificity
- AA 2-109
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TCL1A antibody is un-conjugated
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Application
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Specificity
- T-cell leukemia/Lymphoma Protein 1A (TCL-1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma.
- Cross-Reactivity (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant human TCL1 protein fragment (around aa 2-109) (exact sequence is proprietary)
- Clone
- TCL1-2078
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product TCL1A Primary Antibody
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- Application Notes
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Ramos or Raji cells. Tonsil or T-cell Lymphoma.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))
- Alternative Name
- TCL1A (TCL1A Products)
- Synonyms
- TCL1A antibody, Tcl1a antibody, TCL1 antibody, Tcl1 antibody, T-cell leukemia/lymphoma 1A antibody, T cell lymphoma breakpoint 1 antibody, TCL1A antibody, Tcl1 antibody, Tcl1a antibody
- Background
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TCL1A, Lymphoma/leukemia, T-cell, Oncogene TCL1, P14 TCL1, T cell leukemia 1, T cell lymphoma 1, T cell lymphoma 1A, T-cell leukemia/lymphoma 1A, TCL1, TCL1A,TCL1 (T-Cell Marker)
Cellular localisation: Nuclear and Cytoplasmic - Molecular Weight
- 14kDa
- Gene ID
- 10232, 2484
- UniProt
- P56279
- Pathways
- Stem Cell Maintenance
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