Trefoil Factor 2 antibody (C-Term)

Catalog No. ABIN6938528

Product Details anti-Trefoil Factor 2 Antibody

Target: Trefoil Factor 2 (TFF2)

Binding Specificity: C-Term

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Trefoil Factor 2 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Coating (Coat)

Specificity: Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. The gene encoding pS2 maps to human chromosome 21q22.3.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Synthetic peptide corresponding to a 16-amino acid C-terminal sequence of the human Trefoil factor 2.

Clone: GE16C

Isotype: IgM kappa

Application Details

Application Notes:

Known_Application: ELISA (For coating, order Ab without BSA & Azide),Optimal dilution for a specific application should be determined.

Positive_Control: Human stomach or duodenum tissues (IHC).

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for Trefoil Factor 2

Target: Trefoil Factor 2 (TFF2)

Alternative Name: TFF2 (TFF2 Products)

Synonyms: TFF2 antibody, SML1 antibody, SP antibody, PSP antibody, p4 antibody, p4-a antibody, sml1 antibody, xP4 antibody, xp4.1 antibody, mSP antibody, trefoil factor 2 antibody, trefoil factor 2 S homeolog antibody, trefoil factor 2 (spasmolytic protein 1) antibody, TFF2 antibody, Tff2 antibody, tff2.S antibody

Background: SML1, SP, Spasmolysin, Spasmolytic polypeptide, TFF2, trefoil factor 2 (spasmolytic protein 1), Trefoil factor 2, Trefoil factor 2 precursor,Trefoil factor 2 / TFF2
Cellular localisation: Secreted.

Molecular Weight: 14kDa

Gene ID: 7032, 2979

UniProt: Q03403