TGF-beta antibody

Catalog No. ABIN6938529

The Mouse Monoclonal anti-TGF-beta antibody is suitable to detect TGF-beta in samples from Human, Mouse, Rat, Cow, Dog, Hamster and Monkey. It has been validated for ELISA and Func.

Quick Overview for TGF-beta antibody (ABIN6938529)

Target: TGF-beta (TGFb)

Reactivity: Human, Mouse, Rat, Cow, Dog, Hamster, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This TGF-beta antibody is un-conjugated

Application: ELISA, Functional Studies (Func)

Clone: TGFB-510

Product Details anti-TGF-beta Antibody

Purpose: TGF-beta (Transforming Growth Factor beta) Antibody

Specificity: This MAb recognizes TGF beta 1, 2 and 3. TGF's inhibit the growth of epithelial cells and stimulate the growth of mesenchymal cells.Most breast lesions, benign and malignant, involve abnormal proliferation and altered architecture of stromal and/or epithelial elements.

Cross-Reactivity (Details): Human. Monkey. Cow. Dog. Mouse. Rat. Hamster.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Full length recombinant human TGF-beta2 protein

Isotype: IgG1, kappa

Application Details

Application Notes:

Known_Application: Functional Assay (Order Ab without BSA/Azide), ELISA (0.1-0.4 μg/mL - Detection, 2-8 μg/mL - Capture), Optimal dilution for a specific application should be determined.

Positive_Control: Ovarian carcinoma, lung tumor or skin. PC-3 cell line. Eahy926 cells.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for TGF-beta

Target: TGF-beta (TGFb)

Alternative Name: TFGB

Background:

ARVD, BSC 1 cell growth inhibitor, CED, Cetermin, Diaphyseal dysplasia 1 (DPD1), Glioblastoma derived T cell suppressor factor (G TSF), Latency-associated peptide (LAP), Polyergin, Transforming growth factor beta 1 (TGF beta1 or TGFB1), TGF beta2 (TGFB2), TGF beta3 (TGFB3), TGFbeta (TGFB)

lung tumor or skin. PC-3 cell line. Eahy926 cells., Ovarian carcinoma

Molecular Weight: ~13kDa

Gene ID: 7040, 7042, 7043

UniProt: P01137, P10600, P61812

Pathways: EGFR Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus