BAFF antibody

Catalog No. ABIN6938627

This Mouse Monoclonal antibody specifically detects BAFF in ELISA. It exhibits reactivity toward Human.

Quick Overview for BAFF antibody (ABIN6938627)

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This BAFF antibody is un-conjugated

Application: ELISA

Clone: C257-1638

Product Details anti-BAFF Antibody

Purpose: CD257 / BAFF / TNFSF13B Antibody

Specificity: BAFF/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31 kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN- BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3).

Cross-Reactivity (Details): Human.

Purification: 200ug/ml of Ab Purified from rabbit anti-serum by Protein A.

Immunogen: Purified recombinant human CD257 protein

Isotype: IgG1, kappa

Application Details

Application Notes:

Known_Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

Positive_Control: Jurkat cells. Tonsil and lymph node.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for BAFF

Target: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Alternative Name: TNFSF13B

Background:

ApoL related ligand TALL 1, B lymphocyte stimulator, B-cell-activating factor, BAFF, BLyS, CD257, Dendritic cell-derived TNF-like molecule, DTL, PRO738, TALL-1, THANK, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13b, Tumor necrosis factor ligand superfamily member 20, ZTNF4

Jurkat cells. Tonsil and lymph node.

Molecular Weight: 31kDa (Monomer)

Gene ID: 10673, 525157

UniProt: Q9Y275

Pathways: NF-kappaB Signaling, Production of Molecular Mediator of Immune Response