Uroplakin 3A antibody (AA 260-279)

Catalog No. ABIN6938735

This Rabbit Polyclonal antibody specifically detects Uroplakin 3A in WB. It exhibits reactivity toward Human.

Quick Overview for Uroplakin 3A antibody (AA 260-279) (ABIN6938735)

Target: Uroplakin 3A (UPK3A)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Uroplakin 3A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Uroplakin 3A Antibody

Binding Specificity: AA 260-279

Specificity: Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A

Isotype: IgG

Application Details

Application Notes:

Known_Application: Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: HEK293 cells. Bladder carcinoma.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for Uroplakin 3A

Target: Uroplakin 3A (UPK3A)

Alternative Name: UPK3A

Background: UP3a, UPIIIA, UPK3A, Uroplakin III (UPIII), Uroplakin3A,Uroplakin 3A (Bladder Carcinoma Marker)
Cellular localisation: Cell surface

Molecular Weight: 30kDa

Gene ID: 7380, 632787

UniProt: O75631