YWHAE antibody

Catalog No. ABIN6938792

Product Details anti-YWHAE Antibody

Target: YWHAE (14-3-3 epsilon (YWHAE))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This YWHAE antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificity: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant human full-length YWHAE protein

Clone: CPTC-YWHAE-1

Isotype: IgG2a kappa

Application Details

Application Notes:

Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: HEK-293 or A-431 cell lines.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for YWHAE

Target: YWHAE (14-3-3 epsilon (YWHAE))

Alternative Name: YWHAE (YWHAE Products)

Synonyms: 14-3-3 antibody, 14-3-3 epsilon antibody, 14-3-3-e antibody, 14-3-3-epsilon antibody, 14-3-30epsilon antibody, 14-3-3EPSILON antibody, 14-3-3e antibody, 14-3-3omicron antibody, 1433epsilon antibody, 143E_DROME antibody, CG31196 antibody, CT24092 antibody, D14-3-3e antibody, D14-3-3epsilon antibody, Dmel\\CG31196 antibody, EK3-5 antibody, PAR-5 antibody, PAR5 antibody, Par-5 antibody, SR3-9 antibody, Su(Raf)3B antibody, anon-WO0172774.141 antibody, anon-WO02059370.52 antibody, d14-3-3epsilon antibody, eps antibody, l(3)j2B10 antibody, par-5 antibody, 14-3-3epsilon antibody, kcip-1 antibody, mdcr antibody, mds antibody, LOC581376 antibody, Ywhae antibody, ACYPI002517 antibody, YWHAE antibody, 14-3-3E antibody, KCIP-1 antibody, MDCR antibody, MDS antibody, AU019196 antibody, fe38c12 antibody, wu:fb48f06 antibody, wu:fe38c12 antibody, wu:fi22e10 antibody, ywhae antibody, zgc:55377 antibody, zgc:77062 antibody, CG31196 gene product from transcript CG31196-RD antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon antibody, 14-3-3 epsilon antibody, 14-3-3 epsilon protein antibody, 14-3-3 protein epsilon antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon S homeolog antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1 antibody, 14-3-3epsilon antibody, ywhae antibody, LOC581376 antibody, Ywhae antibody, HCAG_04173 antibody, PTRG_02836 antibody, PTRG_04459 antibody, UREG_07864 antibody, YWHAE antibody, ywhae.S antibody, ywhae1 antibody

Background: MDS, epididymis luminal protein 2, mitochondrial import stimulation factor (MSF) L subunit, Mitochondrial import stimulation factor L subunit, MSF L, protein kinase C inhibitor protein-1,14-3-3E / Tryptophan 5-Monooxygenase
Cellular localisation: Cytoplasm. Melanosome.

Molecular Weight: 29.4kDa

Gene ID: 7531, 513851

UniProt: P62268

Pathways: Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, M Phase