BTLA antibody
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- Target See all BTLA Antibodies
- BTLA (B and T Lymphocyte Associated (BTLA))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This BTLA antibody is un-conjugated
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Application
- ELISA, Coating (Coat)
- Purification
- Purified by Protein A/G
- Immunogen
- Recombinant full-length human BTLA protein
- Clone
- BTLA-1528
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product BTLA Primary Antibody
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anti-B and T Lymphocyte Associated (BTLA) antibody
BTLA Reactivity: Human WB, FACS Host: Mouse Monoclonal 2E4 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 30-183) antibodyBTLA Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 31-157) antibodyBTLA Reactivity: Human WB, ELISA, FACS, IHC, ICC, Neut Host: Mouse Monoclonal 5G1G10 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 179-289) antibodyBTLA Reactivity: Human WB, ELISA, FACS, IHC, ICC, Neut Host: Mouse Monoclonal 7H3E3 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 221-289) antibodyBTLA Reactivity: Human, Mouse WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) antibodyBTLA Reactivity: Human WB, FACS, IF Host: Mouse Monoclonal 2G2 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 101-150) antibodyBTLA Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 30-183) antibodyBTLA Reactivity: Rat WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) antibodyBTLA Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal MIH26 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (C-Term) antibodyBTLA Reactivity: Human WB, ELISA, ICC, IF Host: Rabbit Polyclonal unconjugated
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- Application Notes
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Positive Control: Human lymph node or MDAMB468 xenograft.
Known Application: ELISA (For coating, order antibody without BSA), Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Expiry Date
- 24 months
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- Target
- BTLA (B and T Lymphocyte Associated (BTLA))
- Alternative Name
- BTLA (BTLA Products)
- Synonyms
- BTLA antibody, BTLA1 antibody, CD272 antibody, A630002H24 antibody, B and T lymphocyte associated antibody, BTLA antibody, Btla antibody
- Background
- B and T lymphocyte attenuator (BTLA) is an immunoglobulin domain-containing glycoprotein whose expression is induced during T-cell activation. BTLA is similar to CTLA-4 and PD-1, all of which are coinhibitory receptors belonging to the CD28 family. However, unlike CTLA-4 and PD-1, BTLA does not interact with B7-Ig family counter receptors. Rather, the herpesvirus entry mediator (HVEM), a TNF receptor, acts as a molecular switch that modulates T-cell activation by propagating inhibitory signals through BTLA. The BTLAHVEM interaction is conserved between Mouse and human, suggesting that this system is an important pathway regulating lymphocyte activation.
- Molecular Weight
- 33kDa
- Gene ID
- 151888
- Pathways
- Cancer Immune Checkpoints
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