ICAM-3/CD50 antibody
Quick Overview for ICAM-3/CD50 antibody (ABIN6939683)
Target
See all ICAM-3/CD50 (ICAM3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Recognizes the N-glycosylated glycoprotein of 120 kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3. CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion. It is expressed on thymocytes and T lymphocytes and is resistant to treatment with phosphatidylinositol (PI) phospholipase C.
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Purification
- Purified by Protein A/G
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Immunogen
- Human ICAM3
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Isotype
- IgG1 kappa
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Application Notes
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Positive Control: HL-60 or THP-1 cells. Lymph node and tonsil.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.
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Restrictions
- For Research Use only
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Concentration
- 200 μg/mL
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Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-80 °C
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Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Expiry Date
- 24 months
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- ICAM-3/CD50 (ICAM3) (Intercellular Adhesion Molecule 3 (ICAM3))
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Alternative Name
- ICAM3
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Molecular Weight
- 110-160kDa
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Gene ID
- 3385
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UniProt
- P32942
Target
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