ITGAL antibody
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- Target See all ITGAL Antibodies
- ITGAL (Integrin alpha-L (ITGAL))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ITGAL antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
- Specificity
- Recognizes a protein of 180 kDa, identified as CD11a (Leucocyte Workshop II, Code N202). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses.
- Purification
- Purified by Protein A/G
- Immunogen
- Stimulated human leukocytes
- Clone
- CRIS-3
- Isotype
- IgG2b kappa
- Top Product
- Discover our top product ITGAL Primary Antibody
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- Application Notes
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Positive Control: JY, HUT-78, MOLT-4, HL60, U937 and human leukocytes. Human lymph nodes and tonsils.
Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL) Functional Studies (Order Ab without BSA & Azide), Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Expiry Date
- 24 months
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- Target
- ITGAL (Integrin alpha-L (ITGAL))
- Alternative Name
- ITGAL (ITGAL Products)
- Synonyms
- CD11A antibody, LFA-1 antibody, LFA1A antibody, (p180) antibody, Cd11a antibody, LFA-1A antibody, Ly-15 antibody, Ly-21 antibody, CD11a antibody, ITGAL antibody, integrin subunit alpha L antibody, integrin alpha L antibody, ITGAL antibody, Itgal antibody
- Molecular Weight
- 180kDa
- Gene ID
- 3683
- UniProt
- P20701
- Pathways
- Activated T Cell Proliferation, Integrin Complex
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