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Recombinant Keratin 10 antibody

KRT10 Reactivity: Human, Dog, Cat IHC, StM Host: Mouse Monoclonal rKRT10-1275 unconjugated Recombinant Antibody
Catalog No. ABIN6939901
  • Target See all Keratin 10 (KRT10) Antibodies
    Keratin 10 (KRT10)
    Antibody Type
    Recombinant Antibody
    Reactivity
    • 120
    • 57
    • 50
    • 26
    • 17
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Dog, Cat
    Host
    • 75
    • 48
    • 2
    Mouse
    Clonality
    • 67
    • 58
    Monoclonal
    Conjugate
    • 71
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Keratin 10 antibody is un-conjugated
    Application
    • 80
    • 55
    • 53
    • 39
    • 34
    • 27
    • 15
    • 14
    • 13
    • 11
    • 11
    • 7
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC), Staining Methods (StM)
    Specificity
    This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
    Purification
    Purified by Protein A/G
    Immunogen
    Recombinant full-lenth human KRT10 protein.
    Clone
    RKRT10-1275
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product KRT10 Primary Antibody
  • Application Notes

    Positive Control: A431, HeLa, MCF7 cells. Esophagus or tonsil.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    Expiry Date
    24 months
  • Target
    Keratin 10 (KRT10)
    Alternative Name
    KRT10 (KRT10 Products)
    Synonyms
    BCIE antibody, BIE antibody, CK10 antibody, EHK antibody, K10 antibody, KPP antibody, D130054E02Rik antibody, K1C1 antibody, Krt-1.10 antibody, Krt1-10 antibody, Ka10 antibody, Ker10 antibody, KRT10 antibody, KRT25 antibody, KRT27 antibody, KRT28 antibody, keratin 10 antibody, keratin 10, type I S homeolog antibody, keratin, type I cytoskeletal 25 antibody, KRT10 antibody, Krt10 antibody, krt10.S antibody, LOC101085587 antibody
    Molecular Weight
    56.5kDa
    Gene ID
    3858
    UniProt
    P13645
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