Prolactin antibody (AA 63-201)

Catalog No. ABIN6940401

This Mouse Monoclonal antibody specifically detects Prolactin in IHC. It exhibits reactivity toward Human.

Quick Overview for Prolactin antibody (AA 63-201) (ABIN6940401)

Target: Prolactin (PRL)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Prolactin antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: PRL-2644

Product Details anti-Prolactin Antibody

Binding Specificity: AA 63-201

Purpose: Prolactin (Pituitary Tumor Marker) Antibody

Specificity: Prolactin is a growth factor that is secreted by the anterior pituitary. It is necessary for the proliferation and differentiation of the mammary glands. Prolactin is useful in the classification of pituitary tumors and study of pituitary disease. It also plays a role in the development of mammary cancer, functioning dually as a mitogen and a differentiating agent.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human Prolactin (PRL) protein (around aa 63-201) (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes:

Positive Control: Pituitary.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Prolactin

Target: Prolactin (PRL)

Alternative Name: PRL

Background:

Decidual prolactin, GHA1, Growth hormone A1, Lactogenic hormone, Luteotropic hormone, Mammotropin, PRL, Prolactin, Prolactin precursor

Pituitary.

Molecular Weight: 27kDa

Gene ID: 5617, 1905

UniProt: P01236

Pathways: JAK-STAT Signaling, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Protein targeting to Nucleus