Prolactin Receptor antibody

Catalog No. ABIN6940404

This anti-Prolactin Receptor antibody is a Mouse Monoclonal antibody detecting Prolactin Receptor in IHC, IF, FACS, IHC (p) and StM. Suitable for Human.

Quick Overview for Prolactin Receptor antibody (ABIN6940404)

Target: Prolactin Receptor (PRLR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Prolactin Receptor antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Staining Methods (StM)

Clone: SPM213

Product Details anti-Prolactin Receptor Antibody

Specificity: It recognizes a protein of 70 kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt and water regulation, growth, development and reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases and signal transducers and activators of transcription.

Purification: Purified by Protein A/G

Immunogen: Semi-Purified human prolactin receptor

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: Breast, placenta, liver or pancreas.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin/paraffin tissues requires digestion of tissue sections with pepsin at 1 mg/mL Tris-HCl, pH 2.0 for 15 min at RT or 10 min at 37C.)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Alternative Name: PRLR

Molecular Weight: 70kDa

Gene ID: 5618

UniProt: P16471

Pathways: JAK-STAT Signaling, Response to Growth Hormone Stimulus