TCF4 antibody (AA 365-671)

Catalog No. ABIN6940683

This anti-TCF4 antibody is a Mouse Monoclonal antibody detecting TCF4 in WB, ELISA and Coat. Suitable for Human.

Quick Overview for TCF4 antibody (AA 365-671) (ABIN6940683)

Target: TCF4 (Transcription Factor 4 (TCF4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TCF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Coating (Coat)

Clone: TCF4-1705

Product Details anti-TCF4 Antibody

Binding Specificity: AA 365-671

Specificity: Recognizes a protein of 71 kDa, identified as Transcription Factor 4 (TCF4). It is a basic helix-loop-helix transcription factor. The encoded protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. This gene is broadly expressed and may play an important role in nervous system development. Defects in this gene are a cause of Pitt-Hopkins syndrome.

Purification: Purified by Protein A/G

Immunogen: Recombinant human TCF4 protein fragment (around aa 365-671) (exact sequence is proprietary)

Isotype: IgG2a kappa

Application Details

Application Notes:

Positive Control: HeLa or HepG2 cells. Bladder.

Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Western Blot (1-2 μg/mL)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for TCF4

Target: TCF4 (Transcription Factor 4 (TCF4))

Alternative Name: TCF4

Molecular Weight: 71kDa

Gene ID: 6925

UniProt: P15884

Pathways: WNT Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Regulation of Hormone Metabolic Process, Carbohydrate Homeostasis, Stem Cell Maintenance, Protein targeting to Nucleus