Trefoil Factor 2 antibody (C-Term)

Catalog No. ABIN6940693

The Mouse Monoclonal anti-Trefoil Factor 2 antibody is suitable to detect Trefoil Factor 2 in samples from Human. It has been validated for ELISA.

Quick Overview for Trefoil Factor 2 antibody (C-Term) (ABIN6940693)

Target: Trefoil Factor 2 (TFF2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Trefoil Factor 2 antibody is un-conjugated

Application: ELISA

Clone: GE16C

Product Details anti-Trefoil Factor 2 Antibody

Binding Specificity: C-Term

Purpose: Trefoil factor 2 / TFF2 Antibody

Specificity: Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. The gene encoding pS2 maps to human chromosome 21q22.3.

Purification: 200ug/ml of Ab purified by Protein L.

Immunogen: Synthetic peptide corresponding to a 16-amino acid C-terminal sequence of the human Trefoil factor 2.

Isotype: IgM, kappa

Application Details

Application Notes:

Positive Control: Human stomach or duodenum tissues (IHC).

Known Application: ELISA (For coating, order Ab without BSA & Azide),Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for Trefoil Factor 2

Target: Trefoil Factor 2 (TFF2)

Alternative Name: TFF2

Background:

SML1, SP, Spasmolysin, Spasmolytic polypeptide, TFF2, trefoil factor 2 (spasmolytic protein 1), Trefoil factor 2, Trefoil factor 2 precursor

Human stomach or duodenum tissues (IHC).

Molecular Weight: 14kDa

Gene ID: 7032, 2979

UniProt: Q03403