CD2 antibody

Catalog No. ABIN6941015

This Mouse Monoclonal antibody specifically detects CD2 in FACS, IF and Func. It exhibits reactivity toward Human, Pig, Monkey, Baboon and Chimpanzee.

Quick Overview for CD2 antibody (ABIN6941015)

Target: CD2

Reactivity: Human, Pig, Monkey, Baboon, Chimpanzee

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Clone: RPA-2-10

Product Details anti-CD2 Antibody

Purification: Purified by Protein A/G

Immunogen: Recombinant full-length human CD2 protein

Isotype: IgG1 kappa

Application Details

Application Notes:

Positive Control: 293T or Jurkat cells. Lymph node and tonsil.

Known Application: Functional Studies (Order Ab without Azide), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for CD2

Target: CD2

Alternative Name: CD2

Background: CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

Molecular Weight: 50kDa

Gene ID: 914

UniProt: P06729