GJB1 antibody

Catalog No. ABIN6941303

This Rat Monoclonal antibody specifically detects GJB1 in ELISA. It exhibits reactivity toward Rat and Mouse.

Quick Overview for GJB1 antibody (ABIN6941303)

Target: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Reactivity: Rat, Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This GJB1 antibody is un-conjugated

Application: ELISA

Clone: R5-21C

Product Details anti-GJB1 Antibody

Purpose: Connexin 32 (Gap Junction Protein) Antibody

Specificity: This Ab recognizes a protein of 27-32kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called 'connexons' that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane therefore, one connexin usually cannot fully substitute for another.

Purification: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein G.

Immunogen: Mouse liver DOC-JR-plasma membranes

Isotype: IgG2a, kappa

Application Details

Application Notes:

Positive Control: MCF-7 cells. Pancreas, Liver, Kidney, Stomach or Tonsil.

Known Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA), Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for GJB1

Target: GJB1 (Gap Junction Protein, beta 1, 32kDa (GJB1))

Alternative Name: Gjb1

Background:

Charcot Marie Tooth neuropathy X linked, CMTX, CMTX1, Connexin-32, Cx32, GAP junction 28 kDa liver protein, Gap junction beta-1 protein, Gap junction protein beta 1 32kD, GJB1

Kidney, Liver, MCF-7 cells. Pancreas, Stomach or Tonsil.

Molecular Weight: 27-32kDa

Gene ID: 14618, 21198

UniProt: P28230

Pathways: Cell-Cell Junction Organization