Recombinant 14-3-3 theta antibody (AA 200-300)

Catalog No. ABIN6942014

The Rabbit Monoclonal anti-14-3-3 theta antibody (ABIN6942014) specifically detects 14-3-3 theta in WB. The antibody is reactive with Human samples.

Quick Overview for Recombinant 14-3-3 theta antibody (AA 200-300) (ABIN6942014)

Target: 14-3-3 theta (YWHAQ)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This 14-3-3 theta antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-14-3-3 theta Antibody

Binding Specificity: AA 200-300

Purpose: 14-3-3 Recombinant Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Recombinant protein of Human 14-3-3 between 200-300 amino acids

Isotype: IgG

Application Details

Application Notes: WB(1:500-2000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for 14-3-3 theta

Target: 14-3-3 theta (YWHAQ)

Alternative Name: 14-3-3

Background:

Synonyms: 14-3-3 protein beta/alpha, Protein 1054, Protein kinase C inhibitor protein 1, 14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1, YWHAB, YWHAZ

Background: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.

Gene ID: 7529

UniProt: P31946, P63104

Pathways: Apoptosis, Myometrial Relaxation and Contraction