4E-BP1/2/3 antibody (pThr45)

Catalog No. ABIN6942017

The Mouse Monoclonal anti-4E-BP1/2/3 antibody (Clone 3G2) (ABIN6942017) specifically detects 4E-BP1/2/3 in WB. The antibody is reactive with Human samples.

Quick Overview for 4E-BP1/2/3 antibody (pThr45) (ABIN6942017)

Target: 4E-BP1/2/3

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This 4E-BP1/2/3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 3G2

Product Details anti-4E-BP1/2/3 Antibody

Binding Specificity: pThr45

Purpose: 4E-BP1/2/3 (Thr45) (3G2) Monoclonal Antibody

Cross-Reactivity: Human, Rat

Purification: Purified by Protein A.

Immunogen: Synthetic peptide derived from human 4E-BP1/2/3 (Thr 45), around 35-55aa.

Isotype: IgG2a

Application Details

Application Notes: WB(1:300-5000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for 4E-BP1/2/3

Target: 4E-BP1/2/3

Background:

Synonyms: ABCA1 phospho S2054, p-ABCA1 phospho S2054, ATP binding cassette transporter A1, ABC 1, ABC Transporter 1, ABC1, ABCA 1, ABCA1, ATP binding Cassette 1, ATP binding cassette sub family A ABC1 member 1, ATP binding cassette sub family A member 1, ATP binding cassette sub-family A member 1, ATP binding Cassette Transporter 1, ATP-binding Cassette 1, ATP-binding Cassette Transporter 1, CERP, Cholesterol Efflux Regulatory Protein, FLJ14958, HDLDT1, Membrane bound, MGC164864, MGC165011, TD, TGD, ABCA1_HUMAN.

Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. In humans, this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway. Mutations in the human gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.

Gene ID: 19

UniProt: O95477