Recombinant Acetyl-CoA Carboxylase alpha antibody (AA 350-450)

Catalog No. ABIN6942034

The Rabbit Monoclonal anti-Acetyl-CoA Carboxylase alpha antibody is suitable to detect Acetyl-CoA Carboxylase alpha in samples from Human. It has been validated for WB, IF, IHC (p) and IHC (fro).

Quick Overview for Recombinant Acetyl-CoA Carboxylase alpha antibody (AA 350-450) (ABIN6942034)

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Acetyl-CoA Carboxylase alpha antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Acetyl-CoA Carboxylase alpha Antibody

Binding Specificity: AA 350-450

Purpose: ACACA Recombinant Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Recombinant human ACC1 between 350 to 450 amino acids

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IHC-P(1:20-100), IHC-F(1:100-500), IF()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Acetyl-CoA Carboxylase alpha

Target: Acetyl-CoA Carboxylase alpha (ACACA)

Alternative Name: Acetyl CoA Carboxylase 1(ACC1)

Background:

Synonyms: Acetyl-CoA carboxylase 2, ACC-beta, ACACB, ACC2, ACCB

Background: Catalyzes the ATP-dependent carboxylation of acetyl-CoA to malonyl-CoA. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in inhibition of fatty acid and glucose oxidation and enhancement of fat storage (By similarity). May play a role in regulation of mitochondrial fatty acid oxidation through malonyl-CoA-dependent inhibition of carnitine palmitoyltransferase 1 (By similarity).

Gene ID: 32

UniProt: O00763

Pathways: AMPK Signaling, Ribonucleoside Biosynthetic Process, Warburg Effect