B4GALNT1 antibody (AA 451-533) (FITC)

Catalog No. ABIN6942211

The Rabbit Polyclonal anti-B4GALNT1 antibody is suitable to detect B4GALNT1 in samples from Human. It has been validated for WB, IF (cc) and IF (p).

Quick Overview for B4GALNT1 antibody (AA 451-533) (FITC) (ABIN6942211)

Target: B4GALNT1 (beta-1,4-N-Acetyl-Galactosaminyl Transferase 1 (B4GALNT1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This B4GALNT1 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-B4GALNT1 Antibody (FITC)

Binding Specificity: AA 451-533

Purpose: B4GALNT1/GM2 synthase Polyclonal Antibody, FITC Conjugated

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human B4GALNT1/GM2 synthase

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for B4GALNT1

Target: B4GALNT1 (beta-1,4-N-Acetyl-Galactosaminyl Transferase 1 (B4GALNT1))

Alternative Name: B4GALNT1/GM2 synthase

Background:

Synonyms: (N acetylneuraminyl) galactosylglucosylceramide, (N-acetylneuraminyl)-galactosylglucosylceramide, 4 N-acetylgalactosaminyltransferase 1, 4933429D13Rik, B4GALNT1, B4GN1_HUMAN, Beta 1 4 N acetyl galactosaminyl transferase 1, Beta 1 4 N acetylgalactosaminyltransferase 1, Beta-1, BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE 1, BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE, Beta1 4GalNAc T, Gal-NAc-T, GALGT, Galgt1, GalNAc T, GalNAc-T, GALNACT, GD2 synthase, Ggm-2, Ggm2, GM2 synthase, GM2/GD2 synthase, SIAT 2, SIAT2, UDP Gal:betaGlcNAc beta 1 4 N acetylgalactosaminyltransferase transferase 1, UDP N acetyl alpha D galactosamine:(N acetylneuraminyl).

Background: GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013]

Gene ID: 2583

UniProt: Q00973