Recombinant BANF1 antibody

Catalog No. ABIN6942215

The Rabbit Monoclonal anti-BANF1 antibody (ABIN6942215) specifically detects BANF1 in IF, ICC, IHC (p) and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for Recombinant BANF1 antibody (ABIN6942215)

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This BANF1 antibody is un-conjugated

Application: Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-BANF1 Antibody

Purpose: BANF1 Recombinant Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Full length recombinant protein of human BANF1.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for BANF1

Target: BANF1 (Barrier To Autointegration Factor 1 (BANF1))

Alternative Name: BANF1

Background:

Synonyms: Barrier-to-autointegration factor, Breakpoint cluster region protein 1, Barrier-to-autointegration factor N-terminally processed, BANF1, BAF, BCRG1, NGPS, BCRP1,

Background: Barrier-to-autointegration factor (BANF1) binds non-specifically to double stranded DNA, possibly to play a role in tissue- or cell type-specific gene expression by interacting with different homeodomain transcription factors. BANF1 compresses chromatin structure and interacts with the LEM domain of nuclear proteins to play a crucial role in membrane recruitment and chromatin decondensation during nuclear assembly. Additionally, retroviruses like HIV-1 incorporate BANF1 from host cells into preintegration complexes (PICs) to prevent autointegration of retroviral DNA and thereby promote integration of retroviral DNA into the host chromosome.

Gene ID: 8815

UniProt: O75531