Recombinant CD147 antibody (AA 100-250)

Catalog No. ABIN6942406

The Rabbit Monoclonal anti-CD147 antibody is suitable to detect CD147 in samples from Human, Mouse and Rat. It has been validated for WB, IF, ICC, IHC (p) and IHC (fro).

Quick Overview for Recombinant CD147 antibody (AA 100-250) (ABIN6942406)

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Antibody Type: Recombinant Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD147 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CD147 Antibody

Binding Specificity: AA 100-250

Purpose: CD147 Recombinant Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Human CD147 aa 100-250

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), IHC-P(1 μg/Test), IHC-F(1:50-100), IF(), ICC/IF(1:50-100)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CD147

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Alternative Name: CD147

Background:

Synonyms: Basigin, 5F7, Collagenase stimulatory factor, Extracellular matrix metalloproteinase inducer, Leukocyte activation antigen M6, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor, CD_antigen: CD147, EMMPRIN, TCSF, BSG

Background: Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.

Gene ID: 682

UniProt: P35613

Pathways: S100 Proteins