CENPC1 antibody

Catalog No. ABIN6942503

This anti-CENPC1 antibody is a Rabbit Monoclonal antibody detecting CENPC1 in WB, IF (cc), FACS and IHC (p). Suitable for Human, Mouse and Rat.

Quick Overview for CENPC1 antibody (ABIN6942503)

Target: CENPC1 (Centromere Protein C 1 (CENPC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CENPC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3A7

Product Details anti-CENPC1 Antibody

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Recombinant human CENPC1 protein

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CENPC1

Target: CENPC1 (Centromere Protein C 1 (CENPC1))

Alternative Name: CENPC1

Background:

Synonyms: CENP-C 1, CENP-C, CENPC_HUMAN, CENPC1, Centromere autoantigen C, Centromere autoantigen C1, Centromere protein C 1, ICEN7, Interphase centromere complex protein 7, MIF2.

Background: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPC recruits DNA methylation and DNMT3B to both centromeric and pericentromeric satellite repeats and regulates the histone code in these regions.

Gene ID: 1060

UniProt: Q03188