COX6A1 antibody (AA 25-109)

Catalog No. ABIN6942607

Product Details anti-COX6A1 Antibody

Target: COX6A1 (Cytochrome C Oxidase Subunit VIa Polypeptide 1 (COX6A1))

Binding Specificity: AA 25-109

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX6A1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human COX6A1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for COX6A1

Target: COX6A1 (Cytochrome C Oxidase Subunit VIa Polypeptide 1 (COX6A1))

Alternative Name: COX6A1 (COX6A1 Products)

Synonyms: COX6A antibody, VIA L antibody, VIaL antibody, COX6AL antibody, ns:zf-e250 antibody, zgc:103782 antibody, cox6a antibody, cox6a1-a antibody, cox6a1-b antibody, cox6a1a antibody, cox6al antibody, cytochrome c oxidase subunit VIa antibody, cytochrome c oxidase subunit VIa polypeptide 1 antibody, cytochrome c oxidase subunit 6A1 antibody, cytochrome c oxidase subunit 6A1 L homeolog antibody, COX6A1 antibody, Cox6a1 antibody, cox6a1 antibody, cox6a1.L antibody

Background:

Synonyms: COX VIa L, COX VIa-L, COX6A, COX6A1, COX6AL, CX6A1_HUMAN, Cytochrome c oxidase polypeptide VIa liver, Cytochrome c oxidase polypeptide VIa-liver, Cytochrome c oxidase subunit 6A1, Cytochrome c oxidase subunit 6A1 mitochondrial, Cytochrome C oxidase subunit VIa homolog, Cytochrome c oxidase subunit VIA liver, Cytochrome c oxidase subunit VIa polypeptide 1, Cytochrome c oxidase subunit VIA-liver, MGC104500, mitochondrial.

Background: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66 % amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented. [provided by RefSeq, Jul 2008]

Gene ID: 1337

UniProt: P12074