CPS1 antibody (AA 1351-1500) (Biotin)

Catalog No. ABIN6942623

This anti-CPS1 antibody is a Rabbit Polyclonal antibody detecting CPS1 in ELISA, IHC (p) and IHC (fro). Suitable for Rat.

Quick Overview for CPS1 antibody (AA 1351-1500) (Biotin) (ABIN6942623)

Target: CPS1 (Carbamoyl-Phosphate Synthase 1, Mitochondrial (CPS1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPS1 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CPS1 Antibody (Biotin)

Binding Specificity: AA 1351-1500

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CPS1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CPS1

Target: CPS1 (Carbamoyl-Phosphate Synthase 1, Mitochondrial (CPS1))

Alternative Name: CPS1

Background:

Synonyms: Carbamoyl phosphate synthase [ammonia], Carbamoyl phosphate synthase [ammonia] mitochondrial, Carbamoyl phosphate synthase, Carbamoyl phosphate synthetase 1, Carbamoyl phosphate synthetase 1 mitochondrial, Carbamoyl phosphate synthetase I, Carbamoyl-phosphate synthase [ammonia], Carbamoyl-phosphate synthetase I, Carbamoylphosphate synthase, Carbamoylphosphate synthetase 1, Carbamoylphosphate synthetase I, CPS 1, Cps1, CPSase 1, CPSase I, CPSASE1, CPSM_HUMAN, mitochondrial, MS738.

Background: The mitochondrial enzyme encoded by this gene catalyzes synthesis of carbamoyl phosphate from ammonia and bicarbonate. This reaction is the first committed step of the urea cycle, which is important in the removal of excess urea from cells. The encoded protein may also represent a core mitochondrial nucleoid protein. Three transcript variants encoding different isoforms have been found for this gene. The shortest isoform may not be localized to the mitochondrion. Mutations in this gene have been associated with carbamoyl phosphate synthetase deficiency, susceptibility to persistent pulmonary hypertension, and susceptibility to venoocclusive disease after bone marrow transplantation.[provided by RefSeq, May 2010]

Gene ID: 1373

UniProt: P31327

Pathways: Response to Growth Hormone Stimulus, Cellular Glucan Metabolic Process