CRB1 antibody (AA 301-400)

Catalog No. ABIN6942639

This Rabbit Polyclonal antibody specifically detects CRB1 in IF (cc), IF (p), ELISA, IHC (p), IHC (fro) and ICC. It exhibits reactivity toward Human.

Quick Overview for CRB1 antibody (AA 301-400) (ABIN6942639)

Target: CRB1 (Crumbs Homolog 1 (CRB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRB1 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-CRB1 Antibody

Binding Specificity: AA 301-400

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CRB1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CRB1

Target: CRB1 (Crumbs Homolog 1 (CRB1))

Alternative Name: CRB1

Background:

Synonyms: CRB1, CRUM1_HUMAN, Protein crumbs homolog 1.

Background: This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.[provided by RefSeq, Apr 2012]

Gene ID: 23418

UniProt: P82279

Pathways: Notch Signaling