CRB1 antibody (AA 20-200)

Catalog No. ABIN7266524

The Rabbit Polyclonal anti-CRB1 antibody is suitable to detect CRB1 in samples from Human. It has been validated for WB and IHC.

Quick Overview for CRB1 antibody (AA 20-200) (ABIN7266524)

Target: CRB1 (Crumbs Homolog 1 (CRB1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CRB1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CRB1 Antibody

Binding Specificity: AA 20-200

Purpose: CRB1 Rabbit pAb

Sequence: IYIKNSFCNK NNTRCLSNSC QNNSTCKDFS KDNDCSCSDT ANNLDKDCDN MKDPCFSNPC QGSATCVNTP GERSFLCKCP PGYSGTICET TIGSCGKNSC QHGGICHQDP IYPVCICPAG YAGRFCEIDH DECASSPCQN GAVCQDGIDG YSCFCVPGYQ GRHCDLEVDE CASDPCKNEA T

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-200 of human CRB1 (NP_957705.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CRB1

Target: CRB1 (Crumbs Homolog 1 (CRB1))

Alternative Name: CRB1

Background: This gene encodes a protein which is similar to the Drosophila crumbs protein and localizes to the inner segment of mammalian photoreceptors. In Drosophila crumbs localizes to the stalk of the fly photoreceptor and may be a component of the molecular scaffold that controls proper development of polarity in the eye. Mutations in this gene are associated with a severe form of retinitis pigmentosa, RP12, and with Leber congenital amaurosis. Alternate splicing results in multiple transcript variants, some protein coding and some non-protein coding.,CRB1,LCA8,RP12,CRB1

Molecular Weight: 95kDa/104kDa/142kDa/151kDa/154kDa

Gene ID: 23418

UniProt: P82279

Pathways: Notch Signaling