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CTU2 antibody (AA 301-400) (Cy3)

CTU2 Reactivity: Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal Cy3
Catalog No. ABIN6942731
  • Target See all CTU2 Antibodies
    CTU2 (Cytosolic Thiouridylase Subunit 2 (CTU2))
    Binding Specificity
    • 14
    • 1
    AA 301-400
    Reactivity
    • 15
    • 3
    Mouse
    Host
    • 17
    Rabbit
    Clonality
    • 17
    Polyclonal
    Conjugate
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CTU2 antibody is conjugated to Cy3
    Application
    • 17
    • 12
    • 12
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Cow,Sheep,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CTU2/C16orf84
    Isotype
    IgG
    Top Product
    Discover our top product CTU2 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CTU2 (Cytosolic Thiouridylase Subunit 2 (CTU2))
    Alternative Name
    CTU2 (CTU2 Products)
    Synonyms
    C16orf84 antibody, NCS2 antibody, UPF0432 antibody, Ncs2 antibody, 2310061F22Rik antibody, cytosolic thiouridylase subunit 2 antibody, CTU2 antibody, Ctu2 antibody
    Background

    Synonyms: C16orf84, ctu2, CTU2_HUMAN, Cytoplasmic tRNA 2-thiolation protein 2, cytosolic thiouridylase subunit 2 homolog (S. pombe), NCS2, PF0432.

    Background: CTU2 is a 515 amino acid cytoplasmic protein that plays a role in the 2-thiolation of mcm(5)S(2)U at wobble positions of tRNA. CTU2 forms a complex with CTU1 and Urm1, and may also form a separate heterodimer with CTU1 to ligate sulfur from thiocarboxylated Urm1 onto tRNA. Existing as three alternatively spliced isoforms, the gene encoding CTU2 maps to human chromosome 16q24.3. Chromosome 16 encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

    Gene ID
    348180
    UniProt
    Q2VPK5
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