DCP1A antibody

Catalog No. ABIN6942814

The Rabbit Monoclonal anti-DCP1A antibody is suitable to detect DCP1A in samples from Human. It has been validated for WB, FACS, IHC (p), IF (cc) and IF (p).

Quick Overview for DCP1A antibody (ABIN6942814)

Target: DCP1A (DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This DCP1A antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Clone: 3F4

Product Details anti-DCP1A Antibody

Purpose: DCP1A (3F4) Monoclonal Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000), FCM(1:20-100), IHC-P(1:200-400), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DCP1A

Target: DCP1A (DCP1 Decapping Enzyme Homolog A (S. Cerevisiae) (DCP1A))

Alternative Name: DCP1A

Background:

Synonyms: mRNA-decapping enzyme 1A, Smad4-interacting transcriptional co-activator, Transcription factor SMIF, DCP1A, SMIF

Background: Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1.

Gene ID: 55802

UniProt: Q9NPI6