DHX36 antibody (AA 151-250) (FITC)

Catalog No. ABIN6943000

The Rabbit Polyclonal anti-DHX36 antibody has been validated for WB, IF (cc) and IF (p). It is suitable to detect DHX36 in samples from Mouse and Rat.

Quick Overview for DHX36 antibody (AA 151-250) (FITC) (ABIN6943000)

Target: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHX36 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-DHX36 Antibody (FITC)

Binding Specificity: AA 151-250

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DHX36

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DHX36

Target: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Alternative Name: DHX36

Background:

Synonyms: DDX36, DEAH box protein 36, Dhx36, DHX36_HUMAN, EC 3.6.1.-, KIAA1488, MLE like protein 1, MLE-like protein 1, MLEL1, Probable ATP dependent RNA helicase DHX36, Probable ATP-dependent RNA helicase DHX36, RHAU, RNA helicase associated with AU rich element ARE, RNA helicase associated with AU-rich element ARE.

Background: This gene is a member of the DEAH-box family of RNA-dependent NTPases which are named after the conserved amino acid sequence Asp-Glu-Ala-His in motif II. The protein encoded by this gene has been shown to enhance the deadenylation and decay of mRNAs with 3'-UTR AU-rich elements (ARE-mRNA). The protein has also been shown to resolve into single strands the highly stable tetramolecular DNA configuration (G4) that can form spontaneously in guanine-rich regions of DNA. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Gene ID: 170506

UniProt: Q9H2U1

Pathways: Toll-Like Receptors Cascades