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DHX36 antibody (AA 68-181) (HRP)

DHX36 Reactivity: Human ELISA Host: Rabbit Polyclonal HRP
Catalog No. ABIN7145006
  • Target See all DHX36 Antibodies
    DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))
    Binding Specificity
    • 15
    • 7
    • 6
    • 6
    • 4
    • 3
    • 1
    AA 68-181
    Reactivity
    • 29
    • 26
    • 18
    Human
    Host
    • 44
    Rabbit
    Clonality
    • 44
    Polyclonal
    Conjugate
    • 11
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This DHX36 antibody is conjugated to HRP
    Application
    • 34
    • 20
    • 13
    • 13
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    ELISA
    Cross-Reactivity
    Human
    Purification
    >95%, Protein G purified
    Immunogen
    Recombinant Human ATP-dependent RNA helicase DHX36 protein (68-181AA)
    Isotype
    IgG
    Top Product
    Discover our top product DHX36 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))
    Alternative Name
    DHX36 (DHX36 Products)
    Synonyms
    DHX57 antibody, DDX36 antibody, G4R1 antibody, MLEL1 antibody, RHAU antibody, 2810407E23Rik antibody, AI452301 antibody, AU022184 antibody, Ddx36 antibody, mKIAA1488 antibody, DEAH-box helicase 36 antibody, ATP-dependent RNA helicase DHX36 antibody, DEAH (Asp-Glu-Ala-His) box polypeptide 36 antibody, Dhx36 antibody, DHX36 antibody, dhx36 antibody, LOC100456222 antibody, LOC100633205 antibody
    Background

    Background: Proposed to have a global role in regulating mRNA expression including transcriptional regulation and mRNA stability. Binds with high affinity to and resolves tetramolecular RNA and DNA quadruplex structures. Unwinds intramolecular quadruplexes derived from the ZIC1 and the MYC promoters. Binds to quadruplex structures in the promoters of YY1 and ALPL genes and regulates their expression. Binds to telomerase RNA template component (TERC) 5\'-end (nucleotides 1-43) and unwinds an internal quadruplex formation in TERC 5\'-end to promote P1 helix formation, the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regulation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3\'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis. May play a role in ossification.

    Aliases: DDX36 antibody, DEAH box protein 36 antibody, Dhx36 antibody, DHX36_HUMAN antibody, EC 3.6.1.- antibody, KIAA1488 antibody, MLE like protein 1 antibody, MLE-like protein 1 antibody, MLEL1 antibody, Probable ATP dependent RNA helicase DHX36 antibody, Probable ATP-dependent RNA helicase DHX36 antibody, RHAU antibody, RNA helicase associated with AU rich element ARE antibody, RNA helicase associated with AU-rich element ARE antibody

    UniProt
    Q9H2U1
    Pathways
    Toll-Like Receptors Cascades
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