EDEM3 antibody (AA 401-500)

Catalog No. ABIN6943191

This Rabbit Polyclonal antibody specifically detects EDEM3 in ELISA, IF (cc), IF (p), IHC (fro), IHC (p) and ICC. It exhibits reactivity toward Rat.

Quick Overview for EDEM3 antibody (AA 401-500) (ABIN6943191)

Target: EDEM3 (ER Degradation Enhancer, Mannosidase alpha-Like 3 (EDEM3))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EDEM3 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-EDEM3 Antibody

Binding Specificity: AA 401-500

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Sheep,Pig,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EDEM3

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for EDEM3

Target: EDEM3 (ER Degradation Enhancer, Mannosidase alpha-Like 3 (EDEM3))

Alternative Name: EDEM3

Background:

Synonyms: C1orf22, EDEM 3, edem3, EDEM3_HUMAN, ER degradation enhancer, mannosidase alpha like 3, ER degradation enhancing alpha mannosidase like 3, ER degradation enhancing alpha mannosidase like 3, ER degradation-enhancing alpha-mannosidase-like 3.

Background: Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]).[supplied by OMIM, Mar 2008]

Gene ID: 80267

UniProt: Q9BZQ6

Pathways: SARS-CoV-2 Protein Interactome