EPOR antibody (AA 301-450) (PE)

Catalog No. ABIN6943262

The PE-conjugated Rabbit Polyclonal anti-EPOR antibody (ABIN6943262) specifically detects EPOR in WB. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for EPOR antibody (AA 301-450) (PE) (ABIN6943262)

Target: EPOR (Erythropoietin Receptor (EPOR))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPOR antibody is conjugated to PE

Application: Western Blotting (WB)

Product Details anti-EPOR Antibody (PE)

Binding Specificity: AA 301-450

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EPOR

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EPOR

Target: EPOR (Erythropoietin Receptor (EPOR))

Alternative Name: EPOR

Background:

Synonyms: EPO-R, Erythropoietin receptor, EPOR

Background: Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.

Gene ID: 2057

UniProt: P19235

Pathways: JAK-STAT Signaling