Recombinant F11R antibody (AA 28-241)

Catalog No. ABIN6943391

The Rabbit Monoclonal anti-F11R antibody (ABIN6943391) specifically detects F11R in WB. The antibody is reactive with Human samples.

Quick Overview for Recombinant F11R antibody (AA 28-241) (ABIN6943391)

Target: F11R (F11 Receptor (F11R))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This F11R antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-F11R Antibody

Binding Specificity: AA 28-241

Purpose: F11R/JAM-A/CD321 Recombinant Antibody

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat

Purification: Purified by Protein A.

Immunogen: Human Junctional Adhesion Molecule 1 between 28-241 amino acids

Isotype: IgG

Application Details

Application Notes: WB(WB(1:500-2000))

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for F11R

Target: F11R (F11 Receptor (F11R))

Alternative Name: F11R

Background:

Synonyms: Junctional adhesion molecule A, Junctional adhesion molecule 1, Platelet F11 receptor, Platelet adhesion molecule 1, CD321, JAM-A, JAMA, JAM-1, JAM1, PAM-1, F11R

Background: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly. Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

Gene ID: 50848

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization