Recombinant FTH1 antibody

Catalog No. ABIN6943446

This Rabbit Monoclonal antibody specifically detects FTH1 in WB, IHC (p), IHC (fro) and IF (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant FTH1 antibody (ABIN6943446)

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This FTH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-FTH1 Antibody

Purpose: Ferritin Heavy Chain Recombinant Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: C terminal Human Ferritin Heavy Chain

Isotype: IgG

Application Details

Application Notes: WB(WB(1:500-2000)), IHC-P(IHC-P(1:100-500)), IHC-F(IHC-F(1:100-500)), IF(IHC-P)(IF(IHC-P)(1:100-500))

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FTH1

Target: FTH1 (Ferritin, Heavy Polypeptide 1 (FTH1))

Alternative Name: Ferritin Heavy Chain

Background:

Synonyms: Ferritin heavy chain, Cell proliferation-inducing gene 15 protein, Ferritin heavy chain, N-terminally processed, Ferritin H subunit, FTH1, FTH, FTHL6, FHC, HFE5, PLIF, PIG15

Background: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney.

Gene ID: 2495

UniProt: P02794

Pathways: Transition Metal Ion Homeostasis