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IKZF1 antibody

This anti-IKZF1 antibody is a Rabbit Monoclonal antibody detecting IKZF1 in WB, FACS and IHC (p). Suitable for Human and Mouse.
Catalog No. ABIN6943787

Quick Overview for IKZF1 antibody (ABIN6943787)

Target

See all IKZF1 Antibodies
IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Reactivity

  • 57
  • 38
  • 17
  • 5
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  • 4
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  • 1
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Human, Mouse

Host

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Rabbit

Clonality

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Monoclonal

Conjugate

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  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This IKZF1 antibody is un-conjugated

Application

  • 57
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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

5D4
  • Cross-Reactivity

    Human, Mouse

    Purification

    Purified by Protein A.

    Immunogen

    Recombinant protein within human Ikaros aa 250-450

    Isotype

    IgG
  • Application Notes

    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 μg/μL

    Buffer

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    Preservative

    ProClin

    Precaution of Use

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

    Expiry Date

    12 months
  • Target

    IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

    Alternative Name

    IKZF1

    Background

    Synonyms: DNA-binding protein Ikaros, Ikaros family zinc finger protein 1, Lymphoid transcription factor LyF-1, IKZF1, IK1, IKAROS, LYF1, ZNFN1A1

    Background: Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs). Function is isoform-specific and is modulated by dominant-negative inactive isoforms

    Gene ID

    10320

    UniProt

    Q13422

    Pathways

    Production of Molecular Mediator of Immune Response
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