LAT antibody (pTyr200) (PE)

Catalog No. ABIN6943908

This Rabbit Polyclonal antibody specifically detects LAT in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for LAT antibody (pTyr200) (PE) (ABIN6943908)

Target: LAT (Linker For Activation of T Cells (LAT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LAT antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Product Details anti-LAT Antibody (PE)

Binding Specificity: pTyr200

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human LAT around the phosphorylation site of Tyr200

Isotype: IgG

Application Details

Application Notes: FCM(1:20-100)

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for LAT

Target: LAT (Linker For Activation of T Cells (LAT))

Alternative Name: LAT

Background:

Linker for activation of T cells (LAT) is an integral membrane protein (36 to 38 kD), which plays an important role in linking engagement of the TCR to the biochemical events of T cell activation. LAT antibody stains thymus and peripheral lymphoid tissues such as T cell areas in lymph nodes and spleen. LAT is expressed in T lymphocytes in interstitial spaces, platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells, monocytes, epithelial histiocytes and dendritic cells.

Synonyms: Linker for activation of T cell 1, 36 kDa phospho tyrosine adapter protein, LAT 1, LAT1, Linker for activation of T cells, Linker for activation of T cells family member 1, p36 38, pp36, LAT_HUMAN.

Gene ID: 27040

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway